FICUS SYCOMORUS

\fˈa͡ɪkəs sˈɪkəmˌɔːɹəs], \fˈa‍ɪkəs sˈɪkəmˌɔːɹəs], \f_ˈaɪ_k_ə_s s_ˈɪ_k_ə_m_ˌɔː_ɹ_ə_s]\
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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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