EPIPLOMPHALON

\ˈɛpɪplˌɒmfalən], \ˈɛpɪplˌɒmfalən], \ˈɛ_p_ɪ_p_l_ˌɒ_m_f_a_l_ə_n]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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