CYTOMEGALOVIRUSES
\sˈa͡ɪtə͡ʊmɡˌaləvˌa͡ɪɹəsɪz], \sˈaɪtəʊmɡˌaləvˌaɪɹəsɪz], \s_ˈaɪ_t_əʊ_m_ɡ_ˌa_l_ə_v_ˌaɪ_ɹ_ə_s_ɪ_z]\
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A genus of the family HERPESVIRIDAE, subfamily BETAHERPESVIRINAE, infecting the salivary glands, liver, spleen, lungs, eyes, and other organs, in which they produce characteristically enlarged cells with intranuclear inclusions. Infection with Cytomegalovirus is also seen as an opportunistic infection in AIDS.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.