CONTINUED FRACTION

\kəntˈɪnjuːd fɹˈakʃən], \kəntˈɪnjuːd fɹˈakʃən], \k_ə_n_t_ˈɪ_n_j_uː_d f_ɹ_ˈa_k_ʃ_ə_n]\

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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