CHAINPUMP
\t͡ʃˈe͡ɪnpʌmp], \tʃˈeɪnpʌmp], \tʃ_ˈeɪ_n_p_ʌ_m_p]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.