BURDEN OF ILLNESS

\bˈɜːdən ɒv ˈɪlnəs], \bˈɜːdən ɒv ˈɪlnəs], \b_ˈɜː_d_ə_n ɒ_v ˈɪ_l_n_ə_s]\

Definitions of BURDEN OF ILLNESS

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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