ARCHIMEDEAN SCREW

\ˈɑːkɪmˌɛdi͡ən skɹˈuː], \ˈɑːkɪmˌɛdi‍ən skɹˈuː], \ˈɑː_k_ɪ_m_ˌɛ_d_iə_n s_k_ɹ_ˈuː]\

Definitions of ARCHIMEDEAN SCREW

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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