ABELSON LEUKEMIA VIRUS
\ˈe͡ɪbə͡lsən luːkˈiːmi͡ə vˈa͡ɪɹəs], \ˈeɪbəlsən luːkˈiːmiə vˈaɪɹəs], \ˈeɪ_b_əl_s_ə_n l_uː_k_ˈiː_m_iə v_ˈaɪ_ɹ_ə_s]\
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A replication-defective strain of Murine leukemia virus (LEUKEMIA VIRUS, MURINE) capable of transforming lymphoid cells and producing a rapidly progressing lymphoid leukemia after superinfection with FRIEND, MALONEY, or RAUSCHER MURINE LEUKEMIA VIRUS.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.